--- title: 'Vice President / Senior Vice President, Global Development Leader at Nurix' canonical: 'https://feeny.ai/job/vice-president-senior-vice-president-global-development-leader-nurix-brisbane-8733m03gnsjq' type: 'job' last_seen: '2026-10-29' --- # Vice President / Senior Vice President, Global Development Leader at Nurix - **Company:** Nurix - **Location:** Brisbane, CA - **Posted:** 2026-08-28 - **Last confirmed live:** 2026-10-29 - **Apply:** https://job-boards.greenhouse.io/nurix/jobs/8756817002 ## Job description Vice President / Senior Vice President, Global Development Leader (Bexobrutideg) Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease. We are seeking a brilliant, organized and highly motivated leader who will provide strategic and tactical medical leadership and will deliver key clinical and scientific leadership to clinical development programs while ensuring the highest standard for safety and compliance with regulatory requirements and standard procedures. The ideal candidate should have experience working in a fast-paced dynamic environment.  The successful candidate will report to the Chief Medical Officer.  The responsibilities of this leader are listed below. - Lead one or more Program teams comprised of functional representatives from Clinical Development (Clinical Operations, Medical Monitoring, Clinical Science), Research and Translational Medicine, Regulatory, Technical Operations, Quality, and Commercial from phase 1  through phase 3 and through approval and launch; serve as the single point of accountability for the BTK Program Global Development Team (GDT), and to create and drive key program decisions through appropriate governance forums, where appropriate - As a member of the Clinical Executive Management Team, partner with stakeholders to set clear direction and execute against goals for a portfolio of clinical stage therapies, ensuring the development and execution of program strategy is in line with corporate strategy and goals - Drive the development and communication of program plans and development plan in partnership with the asset teams and program management - Facilitate cross-functional communication; drive strategic and operational alignment with the Program team, functional leads, and Executive Management Team - Identify challenges and risks and prepare the team with mitigations to navigate through technical and program challenges as they arise - Develop or participate in the refinement/update of the Clinical Development Plan (CDP); act as or oversee the clinical leads for protocols and supportive activities to meet the CDP objectives - Provide medical oversight for ongoing clinical trials including regular review of clinical data to improve understanding of the molecule profile, including but not limited to safety and activity - Provide clinical oversight for Company operational staff and contract research organizations (CROs) in all areas related to the execution of therapeutic programs - Provide and or oversee training and ongoing input to all members of the clinical team on medical and scientific issues related to the appropriate therapeutic field - Provide medical support for all relevant regulatory discussions and activities, such as IND’s and NDA/MAAs - Interact with principal investigators and opinion leaders to facilitate clinical trials research - Refine and or establish processes and methods for design and implementation of applicable clinical protocols, data collection systems and final reports - Data presentation to executive leaders, internal and external medical colleagues in one on one or large group settings (50+). Required Qualifications - MD, board certified preferably in hematology/oncology - Requires at least 10 years’ clinical trial experience in the setting of pharmaceutical industry with demonstrated experience and involvement in clinical trial design or execution. In particular, Ph3 clinical trial planning and execution. - Relevant clinical research experience in academic settings will be reviewed in light of clinical development experience - Excellent communicator with proven leadership skills and the ability to interact in a cross functional environment - Comfortable in a fast-paced small company environment with minimal direction and able to adjust workload based upon changing priorities - Proven leadership experience leading high performing teams and individuals - Hands on leadership approach will be best suited for this critical role - Experience working in a highly productive and high achieving collaboration Fit with Nurix Culture and Values - Strong team orientation; highly collaborative - Solutions and results-oriented focus - Hands-on approach; resourceful and open to diverse points of view ## About Nurix ## Company Overview - **One-liner**: Nurix Therapeutics is a clinical-stage biopharmaceutical company pioneering targeted protein degradation medicines to outmatch disease by harnessing the cell’s natural protein disposal system. - **Entity Type**: Public (NASDAQ: NRIX) - **Headquarters**: San Francisco, California, USA - **Founded**: 2009 - **Founders**: Not publicly listed as individual founders; the company was spun out from research at UC Berkeley and UC San Francisco. ## Core Business - **Primary industry**: Biopharmaceuticals / Targeted Protein Degradation - **Target customers**: B2B (pharma partners) and B2C (patients via clinical trials and eventual commercial therapies); enterprise-level partnerships with major pharma. - **Mission or purpose statement**: "Writing medicine’s next chapter using targeted protein degradation as a new script to outmatch disease." [nurixtx.com](https://www.nurixtx.com/) ## Products & Services - **Bexobrutideg (NX-5948)**: A potential best-in-class BTK degrader in Phase 1b/2 clinical trials for relapsed/refractory CLL/SLL and chronic spontaneous urticaria. Co-developed and co-commercialized with Roche under a global collaboration announced June 2026. [nurixtx.com](https://www.nurixtx.com/) - **NX-2127**: A BTK degrader in clinical development for B-cell malignancies. - **CBL-B Inhibitor (NX-1607)**: An E3 ligase inhibitor designed to activate T cells for immuno-oncology, in Phase 1 clinical trials. - **IRAK4 Degrader**: A partnered program with Gilead in Phase 1 for inflammatory diseases. - **STAT6 Degrader**: A partnered program with Sanofi in IND-enabling studies. - **DEL-AI Discovery Engine**: A proprietary, fully AI-integrated platform combining DNA-encoded libraries (DEL), automated chemistry, and machine learning to design and optimize targeted protein degraders and degrader-antibody conjugates (DACs). ## Market Standing - **Valuation/Market Cap**: Not publicly available in the provided search results; as a public company (NRIX), market cap fluctuates daily. Check financial platforms for the latest figure. - **Key Metric**: Annual Revenue (public) — Not publicly available in the provided search results; as a clinical-stage biotech, revenue is typically minimal or pre-revenue. Total funding raised prior to IPO is not detailed in the provided results. - **Notable Investors/Partners**: Roche (global co-development and co-commercialization collaboration for bexobrutideg, announced June 2026), Gilead (partnered IRAK4 degrader program), Sanofi (partnered STAT6 degrader program). - **Growth Signals**: Announced a landmark global collaboration with Roche in June 2026 to co-develop and co-commercialize bexobrutideg across malignant hematology, immunology, and neurology. Presented positive Phase 1a/b data for bexobrutideg in CLL/SLL and chronic spontaneous urticaria in 2026. Multiple partnered and wholly owned pipeline programs advancing through clinical and preclinical stages. ## Competitive Advantages - **Proprietary DEL-AI Discovery Engine**: A fully AI-integrated platform combining DNA-encoded libraries, automated chemistry, and machine learning to design degraders against any protein class, providing a significant speed and innovation advantage. [nurixtx.com](https://www.nurixtx.com/) - **Unparalleled Ligase Expertise**: Deep understanding of E3 ligase biochemistry and biology, a critical and complex component of the protein degradation mechanism, giving them a unique moat. - **Multi-Modal Pipeline**: Developing both small molecule degraders and Degrader-Antibody Conjugates (DACs), expanding the therapeutic reach and creating multiple shots on goal. - **Strong Partnership Network**: Collaborations with top-tier pharma (Roche, Gilead, Sanofi) validate their platform and provide non-dilutive funding and shared risk. ## Strategic Focus - **Clinical Advancement**: Driving lead asset bexobrutideg through pivotal trials in CLL/SLL and expanding into immunology (chronic spontaneous urticaria) and neurology. - **Platform Expansion**: Leveraging the DEL-AI engine to develop Degrader-Antibody Conjugates (DACs) for enhanced cell specificity and safety. - **Pipeline Breadth**: Advancing a multi-modal pipeline across oncology, immunology, and neurology, both wholly owned and through strategic partnerships. - **Partnership Leverage**: Deepening collaborations with Roche, Gilead, and Sanofi to co-develop and co-commercialize programs, reducing risk and accelerating timelines. ## Why Work Here - **Culture**: Mission-focused, values-based, and spirited culture emphasizing "breakthrough innovation," "leadership," "accountability," and "zealousness." Employees are encouraged to "think big and act bold." [nurixtx.com](https://www.nurixtx.com/work-at-nurix/) - **Work with Industry Leaders**: The team includes scientific innovators who built the protein degradation field, seasoned executives with biotech scaling expertise, and leading clinicians. [nurixtx.com](https://www.nurixtx.com/work-at-nurix/) - **Growth & Impact**: Employees can "wear many hats" and gain broad exposure in a lean, virtual drug developer environment. The company emphasizes career growth and opportunity-rich experiences. - **Work Policy**: Onsite in Brisbane, CA (San Francisco Bay Area) for most roles, as indicated by job postings. [nurixtx.com](https://www.nurixtx.com/explore-jobs/) - **Benefits**: Comprehensive health and welfare plans, enhanced parental leave, wellness reimbursement, 401(k) employer match, and a highly collaborative culture. [nurixtx.com](https://www.nurixtx.com/work-at-nurix/) - **Engineering/Science Culture**: Described as "mission-focused, values-based, and spirited," with a focus on "intellectual and technical ingenuity" and "intelligent risk-taking." The company is a "virtual drug developer" with a lean internal infrastructure, relying on SaaS and cloud platforms. [nurixtx.com](https://www.nurixtx.com/explore-jobs/) ## Sources 1. [nurixtx.com](https://www.nurixtx.com/) 2. [nurixtx.com](https://www.nurixtx.com/work-at-nurix/) 3. [nurixtx.com](https://www.nurixtx.com/explore-jobs/) 4. [nurixtx.com](https://www.nurixtx.com/our-story/) ## Other roles at Nurix - [Director, Quality Assurance](https://feeny.ai/job/director-quality-assurance-nurix-brisbane-3g1nz641gtdv) — Brisbane, CA - [Senior/Principal Scientist, Medicinal Chemistry](https://feeny.ai/job/senior-principal-scientist-medicinal-chemistry-nurix-brisbane-sk240f67bwms) — Brisbane, CA - [Scientist I, Bioanalytical](https://feeny.ai/job/scientist-i-bioanalytical-nurix-brisbane-tns4szvd5c07) — Brisbane, CA - [Senior Research Associate, Preclinical Pharmacology](https://feeny.ai/job/senior-research-associate-preclinical-pharmacology-nurix-brisbane-whtmqmhser7g) — Brisbane, CA - [Senior Scientist, Medicinal Chemistry](https://feeny.ai/job/senior-scientist-medicinal-chemistry-nurix-the-woodlands-y4nmgjxktsm5) — The Woodlands, TX - [Scientist I, Medicinal Chemistry](https://feeny.ai/job/scientist-i-medicinal-chemistry-nurix-the-woodlands-bxgy2c1m60vz) — The Woodlands, TX - [Senior Director, Head of Pharmacovigilance Operations](https://feeny.ai/job/senior-director-head-of-pharmacovigilance-operations-nurix-brisbane-qvx5sf5gc0cv) — Brisbane, CA - [Senior Manager / Associate Director, Regulatory Affairs CMC (Small Molecules)](https://feeny.ai/job/senior-manager-associate-director-regulatory-affairs-cmc-small-molecules-nurix-pp3fh8jc68k1) — Brisbane, CA - [Administrative Assistant, Clinical Development (Contract)](https://feeny.ai/job/administrative-assistant-clinical-development-contract-nurix-brisbane-6rnsp2fj2vte) — Brisbane, CA - [Administrative Assistant, CMC (Contract)](https://feeny.ai/job/administrative-assistant-cmc-contract-nurix-brisbane-cgkssyzb35sq) — Brisbane, CA