--- title: 'VP, Human Resources at Quantum-Si' canonical: 'https://feeny.ai/job/vp-human-resources-quantum-si-san-diego-vne9z1bstxcr' type: 'job' last_seen: '2026-09-09' --- # VP, Human Resources at Quantum-Si - **Company:** Quantum-Si - **Location:** San Diego, CA - **Posted:** 2026-08-31 - **Last confirmed live:** 2026-09-09 - **Apply:** https://job-boards.greenhouse.io/quantumsi25/jobs/6175303004 ## Job description The Vice President, Human Resources serves as a hands-on strategic business partner to executive leadership and leads all aspects of the people function, including talent acquisition, total rewards, employee relations, performance management, leadership development, culture, engagement, HR operations, and compliance. This role develops and executes people strategies that support business objectives while ensuring an exceptional employee experience. As part of our team, your core responsibilities will be: - Develop and execute the company's global people strategy in support of business objectives and long-term growth. - Serve as a trusted advisor to the CEO and executive leadership team on talent, organizational effectiveness, culture, succession planning, and workforce strategy. - Provide strategic leadership and oversight of all Human Resources functions, including talent acquisition, payroll and benefits, HR operations, employee relations, performance management, learning and development, engagement, and compliance. - Partner with business leaders to design organizational structures that enable scalability, efficiency, and achievement of strategic goals. - Partner with the CEO and CFO to design and implement compensation, equity, and benefits programs to ensure competitive, equitable, and fiscally responsible rewards practices. - Support Compensation Committee activities, including market benchmarking, plan design, and governance - Develop and implement talent management and succession planning processes to build leadership capability across the organization. - Sponsor and champion performance management, leadership accountability, employee development, and recognition programs across the organization. - Ensure compliance with employment laws and regulations in all jurisdictions where the company operates. - Provide strategic guidance on complex employee relations matters, workplace investigations, risk management, and policy development efforts. - Champion employee engagement, inclusion, and company culture initiatives that support attraction, retention, and productivity. - Manage workforce planning, restructuring activities, change management initiatives, and organizational transformations. - Establish HR metrics and analytics to guide decision-making and measure the effectiveness of people programs. - Build, mentor, and develop a high-performing HR team while fostering operational excellence and continuous improvement. - Oversee HR systems, processes, and controls to ensure efficient, scalable, and compliant operations. ## Qualifications - Bachelor's degree in Human Resources, Business Administration, Organizational Development, Psychology, or a related field. - 10+ years of progressive Human Resources experience, including significant leadership responsibility across multiple HR disciplines. - 7+ years of experience leading HR teams in a fast paced, growing or complex organization. - Proven ability to lead in a hands-on, collaborative manner while balancing strategic priorities and day-to-day execution; prior experience in a start-up is helpful. - Demonstrated success partnering with executive leadership teams to align people strategies with business objectives. - Experience leading core HR functions, including talent acquisition, total rewards, performance management, employee relations, organizational development, compliance, and HR operations. - Strong knowledge of federal and state employment laws and HR compliance requirements. - Experience with managing a global PEO or EOR and leading global HR programs and supporting international employees. - Proven ability to lead organizational change, workforce planning, restructuring initiatives, and culture transformation efforts. - Experience developing and implementing compensation, equity, and incentive programs. - Strong analytical and business acumen with the ability to leverage people metrics to inform decisions. - Excellent executive presence, communication, and stakeholder management skills. - Ability to influence senior leaders and drive results through collaboration and accountability. - Ability to travel up to 25% of the time. ## Preferred Qualifications - Experience supporting a public company environment. - Experience working with Compensation Committees and Board-level governance matters. - Background in biotechnology, life sciences, med-tech or healthcare - HR certification such as PHR, SPHR, SHRM-CP, or SHRM-SCP preferred. The estimated base salary range for this position in the United States is $250,000 - $275,000. In addition to base salary, full-time employees are eligible to participate in Quantum-Si's discretionary annual bonus program and may receive equity awards as part of the total compensation package. Actual compensation will be determined based on a variety of factors, including, but not limited to, the position level, relevant skills, knowledge, experience, qualifications, geographic location, internal equity, and market data. Quantum-Si also offers a competitive benefits package designed to support employees' health, well-being, work-life balance, and family needs. Benefits include: - Comprehensive medical, dental, and vision insurance coverage - Health Savings Account (HSA) and Flexible Spending Account (FSA) options, where applicable - Company-paid life and accidental death & dismemberment (AD&D) insurance - Short-term and long-term disability coverage - Employee Assistance Program (EAP) resources to support personal and professional well-being - Discretionary paid time off and company-paid holidays - Parental leave to support employees welcoming and caring for a new child - 401(k) retirement savings plan with both pre-tax and Roth contribution options Additional Information Candidates must be authorized to work in the United States. Quantum-Si does not provide employment-based immigration sponsorship of any kind for this position, including support for applicants currently pursuing permanent residency (Green Card sponsorship). Quantum-Si does not accept unsolicited agency resumes. Quantum-Si is an E-Verify and equal opportunity employer regardless of race, color, ancestry, religion, gender, national origin, sexual orientation, age, citizenship, marital status, disability or Veteran status. All your information will be kept confidential according to EEO guidelines. ## About Quantum-Si ## Company Overview - **One-liner**: Quantum-Si is pioneering the post-genomic era by making single-molecule protein sequencing accessible through its benchtop Platinum and Platinum Pro instruments. - **Entity Type**: Public (NASDAQ: QSI) - **Headquarters**: Branford, Connecticut, United States - **Founded**: 2013 - **Founders**: Jonathan Rothberg ## Core Business - **Primary industry**: Biotechnology Research / Life Sciences Tools (Proteomics) - **Target customers**: B2B; academic research labs, pharmaceutical and biotechnology companies, core facilities, and drug development organizations. - **Mission or purpose statement**: To power the post-genomic era of biology by making next-generation protein sequencing (NGPS) accessible to every lab, everywhere, enabling breakthroughs in drug discovery, diagnostics, and human health. ## Products & Services - **Platinum® Pro**: An advanced benchtop next-gen protein sequencer (NGPS) delivering single-molecule resolution with real-time kinetic insights. It features a simplified workflow (less than three hours of hands-on time), a user-friendly touchscreen interface, and flexible data analysis (local or cloud-based). Designed for variant detection, protein identification, and post-translational modification (PTM) analysis. - **Platinum®**: The world’s first next-gen protein sequencing instrument, enabling single-molecule, single-amino-acid resolution for proteomics research. - **Proteus™ Platform**: A next-generation platform (announced in partnership with Cell Signaling Technology) focused on advancing post-translational modification (PTM) analysis. - **Protein Barcoding**: A solution for simultaneously characterizing multiple protein variants, increasing throughput for screening and therapeutic development, including applications in drug delivery (LNPs, AAV capsids) and antibody characterization. ## Market Standing - **Valuation/Market Cap**: $109.7 million (as of mid-2026) [linkedin.com] - **Key Metric**: Annual Revenue of $2.4 million (public company) [linkedin.com] - **Total Funding**: $1.065 billion (including post-IPO equity rounds) [linkedin.com] - **Notable Investors/Partners**: HighCape Capital Acquisition Corp (parent), Cell Signaling Technology (strategic partner for PTM analysis), 4Catalyzer (affiliated incubator). - **Growth Signals**: - Publicly traded on NASDAQ (QSI) since June 2021. - Announced a strategic partnership with Cell Signaling Technology in June 2026 to advance PTM analysis on the Proteus platform [quantum-si.com]. - Expanding commercial presence with a roadshow for the Proteus platform [quantum-si.com]. - Named "2023 Proteomics Company of the Year" and "Innovation by Design 2023" [quantum-si.com]. - Active hiring for senior commercial and field roles, indicating a push to scale go-to-market. ## Competitive Advantages - **First-mover in NGPS**: Quantum-Si is the first company to bring a next-generation protein sequencing (NGPS) platform to market, offering single-molecule resolution that traditional mass spectrometry and Edman degradation cannot achieve. - **Simplified Workflow**: The platform requires less than three hours of hands-on time and no dedicated lab space or specialized expertise, making advanced proteomics accessible to a broader range of labs. - **Unique Kinetic Profiling**: Uses real-time, single-molecule kinetic signatures to detect protein variants, post-translational modifications, and proteoforms, providing deeper functional insights than antibody-based or mass-spec methods. - **Integrated AI**: Blends biology, chemistry, and artificial intelligence to drive data analysis and interpretation. ## Strategic Focus - **Commercial Expansion**: Scaling the commercial team (hiring field application scientists, service engineers, and business development managers) to drive adoption of the Platinum and Proteus platforms globally. - **Partnership Development**: Deepening collaborations with key players like Cell Signaling Technology to expand applications in PTM analysis and drug development. - **Platform Evolution**: Advancing the Proteus platform and expanding the protein barcoding solution for high-throughput screening in therapeutic development (e.g., LNPs, AAV capsids). - **Market Penetration**: Moving beyond early adopters to broader academic and pharmaceutical markets, with a focus on making proteomics accessible without dedicated lab space or specialized expertise. ## Why Work Here - **Culture**: Described as dynamic, collaborative, and purpose-driven, with a focus on innovation and solving complex scientific challenges. Values include "Never Settle," "Embrace Change," "Succeed Together," "Stand Up," and "Speak Up" [quantum-si.com]. - **Mission-Driven**: Employees are motivated by the potential to transform human health and make a global impact through accessible protein sequencing. - **Benefits & Perks**: 100% fully covered medical/dental/vision, generous HSA contribution on HDHP, 401K plan, generous parental leave, flexible paid time off, short/long-term disability, and company-sponsored life insurance [quantum-si.com]. - **Equity**: 100% of employees are stakeholders, aligning team members with company success. - **Work Environment**: Dynamic and collaborative culture. Roles are a mix of on-site (San Diego, CA; Branford, CT) and remote (e.g., Field Application Scientist, Northwest AMR). The company emphasizes transparency, adaptability, and a purpose-driven mission. - **Headcount**: 153 employees, with a +1.6% YoY growth. The team is primarily US-based (75%) with a presence in France, UK, Germany, Spain, Belgium, and Singapore [linkedin.com]. ## Sources 1. [quantum-si.com](https://www.quantum-si.com/) 2. [quantum-si.com/about](https://www.quantum-si.com/about/) 3. [quantum-si.com/careers](https://www.quantum-si.com/about/careers/) 4. [linkedin.com/company/quantum-si](https://www.linkedin.com/company/quantum-si) 5. 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