---
title: 'VP, US Site Management & Operations - GI at Iterative Health'
canonical: 'https://feeny.ai/job/vp-us-site-management-operations-gi-iterative-health-new-york-mzp6n6cw94dr'
type: 'job'
last_seen: '2026-09-11'
---

# VP, US Site Management & Operations - GI at Iterative Health

- **Company:** Iterative Health
- **Location:** New York, NY / Boston, MA / Dallas, TX
- **Posted:** 2026-09-01
- **Last confirmed live:** 2026-09-11
- **Apply:** https://job-boards.greenhouse.io/iterativehealth/jobs/4709061006

## Job description

Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes.

We built a leading performance-driven network of 100+ sites across the US, Europe, India, and Australia, conducting research directly in the communities where care is delivered across gastrointestinal, hepatology, obesity, and cardiology. By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ambitions with high-performing research teams that expedite and expand access to novel therapeutics for patients in need. Today, Iterative Health is headquartered in Cambridge, Massachusetts, and New York City with 250+ employees world-wide.

As the VP, US Site Management & Operations at Iterative Health, you will lead the performance, growth, and operational excellence of our GI and Hepatology network of clinical research sites across the United States.

You’ll be accountable for the performance and P&L of 50+ US-based sites, driving research revenue as a meaningful growth engine and building the operational excellence that makes our sites the best place to run a clinical trial. You’ll set the strategy and operating model to scale the network while delivering exceptional experiences for patients, Principal Investigators, sponsors, and study teams.

This is a hands-on executive leadership role with direct accountability for results. You’ll lead a team of Regional Directors who oversee Site Managers, Clinical Research Coordinators, Research Assistants, and other research professionals, while partnering closely with Principal Investigators and leaders across the organization to drive performance, growth, and scale.

Where You’ll Drive Impact

Site Performance & Management

- Own site health, revenue, P&L, and operational performance across Iterative Health’s US GI site network.
- Establish clear reporting, performance benchmarks, and action plans to drive continuous improvement and sustainable growth of our sites.
- Proactively identify performance gaps and partner across functions to address barriers to revenue, productivity, capacity, and study execution.
- Own staffing strategy across the network, partnering with the People Team to ensure sites are appropriately staffed and positioned for growth.
- Oversee day-to-day site operations, capacity, and study portfolio management, ensuring the right studies are matched to the right sites and that sites are positioned to maximize enrollment and research revenue.
- Identify opportunities to expand site capabilities, capacity, and research volume across the GI and Hepatology network.
- Drive enrollment, data quality, compliance, and overall study execution against premium network benchmarks.
- Ensure teams are aligned, appropriately resourced, and accountable for delivering study and network commitments and operational targets.
- Own the site operations workstream for M&A integrations, partnering with cross-functional leaders to assess operational readiness, integrate acquired sites and teams, align processes and systems, and ensure a seamless transition into the Iterative Health operating model.
- Partner closely with Site Solutions, Study Success, Life Sciences, Finance, People, Product,, and other key stakeholders to align site strategy, resources, and execution with broader company objectives.

Deep Site Relationships & People Management

- Build deep relationships with key Principal Investigators and establish a consistent standard for PI engagement across the network..
- Build relationships with the broader practice, including practice leadership to drive engagement and buy-in to research
- Build a culture of ownership, accountability, development, and retention through strong leadership, training, and career development for site level staff
- Additional responsibilities as needed to support the company’s strategic priorities.

## What You Bring to the Team

- 12+ years of progressive leadership experience in healthcare, clinical research, healthcare services or related field in a multi-site organization.
- Bachelor’s degree required; advanced degree in healthcare, business, life sciences, or a related field preferred.
- Proven experience building, scaling, or transforming a healthcare service line, business unit, or multi-site operation in a high-growth environment.
- Demonstrated ownership of P&L, revenue growth, operational performance, and resource allocation.
- Experience participating in M&A, acquisitions, integrations, or organizational transformation strongly preferred.
- Strong understanding of clinical research and/or healthcare operations, with GI experience a plus.
- Proven ability to translate strategy into execution and drive measurable results across distributed organizations.
- Exceptional people leadership skills, with experience building teams, developing leaders, and fostering accountability and high performance.
- Strong track record of building trusted relationships with clinicians and senior stakeholders and driving alignment across diverse groups.
- Demonstrated success partnering cross-functionally across Operations, Finance, Commercial/Business Development, and People to build and scale a business.
- Entrepreneurial, hands-on leadership style with the ability to operate strategically while staying close to execution in a high-growth environment.

## How We Work

- Collaborative and low-ego team environment
- High ownership and accountability culture
- Fast-paced and highly iterative growth environment
- Open communication and continuous learning mindset
- Mission-driven organization focused on improving patient outcomes
- Comfortable navigating evolving business priorities and opportunities

## Benefits That Support You

We believe great teams do their best work when they feel supported — professionally and personally.

- Hybrid work environment with in-office collaboration two days per week in either our NYC,  Boston or Southlake office
- Comprehensive medical, dental, and vision coverage, with up to 80% of premiums covered by Iterative Health
- Mental health and wellness support through Spring Health
- Health HSA or FSA options, and commuter FSA contributions supported by Iterative Health
- Unlimited PTO, 12 company holidays, and a company-wide shutdown between Christmas and New Years
- 401(k) program with a company match of up to 3% (up to $3,000 annually)
- Weekly in-office lunch benefit every Tuesday
- 100% company-paid short-term and long-term disability coverage
- Annual wellness and professional development stipend to support your health and growth

At Iterative Health, we’re actively working towards creating an environment that is representative of the diversity of patients our technology serves. We are focused on building an equitable and inclusive culture, and by extension, hiring process. If you require any accommodations to make the application process or interviewing experience more accessible to you, please contact CandidateAccommodations@iterative.health.

## About Iterative Health

## Company Overview
- **One-liner**: Iterative Health is a healthcare technology and services company that accelerates clinical research by combining AI-powered tools with a performance-driven global site network, focusing on GI, Hepatology, Obesity, and Cardiology therapies.
- **Entity Type**: Private (Series C)
- **Headquarters**: Cambridge, Massachusetts, United States (also New York, New York)
- **Founded**: 2017
- **Founders**: Jonathan Ng, MBBS (Founder & CEO)

## Core Business
- **Primary industry/industries**: Healthcare technology, clinical research services, artificial intelligence
- **Target customers**: B2B – sponsors (pharma/biotech), CROs, and community-based provider networks (clinical research sites)
- **Mission or purpose**: “To accelerate clinical research to bring life-changing therapies to patients sooner, transforming care through expertise and proven results.”

## Products & Services
- **AI-Powered Clinical Trial Platform**: Software that streamlines site selection, patient enrollment, and operational workflows, reducing burden and accelerating trial timelines.
- **Performance-Driven Site Network**: A global network of elite community-based research sites with deep expertise in GI, Hepatology, Obesity, and Cardiology, enabling faster activation and high enrollment.
- **Site Enablement Services**: Operational support, training, and technology to help sites grow their research programs and improve performance.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed (private company)
- **Key Metric**: Total Funding – $264 million (including $77 million Series C closed May 2026)
- **Notable Investors/Partners**: Partners include GI Alliance, One GI, and US Heart & Vascular (USHV). Specific investors not named in provided materials, but Series C led by investors noted in Business Wire (May 14, 2026).
- **Growth Signals**: 
  - Raised $77M Series C in May 2026 to accelerate clinical research.
  - Acquired cardiology research sites from NextStage Clinical Research (April 2026), expanding into cardiology.
  - Presented expanded trial performance data at Digestive Disease Week 2026, demonstrating consistent outperformance of industry benchmarks at double the scale.

## Competitive Advantages
- **Deep Therapeutic Focus**: Specialized expertise in GI, Hepatology, Obesity, and Cardiology allows for tailored site selection and patient recruitment that generalist CROs cannot match.
- **AI Integration**: Proprietary AI tools that enhance site selection, pre-screening, and operational efficiency, reducing time-to-market for sponsors.
- **Embedded Community Network**: Sites are integrated into community care settings, giving access to diverse patient populations and enabling faster, more representative enrollment.
- **Performance Track Record**: Proven ability to activate sites faster and achieve industry-leading enrollment metrics, as validated by DDW 2026 data.

## Strategic Focus
- **Scale the Site Network**: Continue acquiring and onboarding high-performing community sites, particularly in cardiology and other adjacent therapeutic areas.
- **Deepen AI Capabilities**: Invest in machine learning and data science to further automate and optimize clinical trial operations.
- **Expand Sponsor Partnerships**: Leverage the combined technology and site network to become the preferred partner for sponsors seeking rapid, reliable trial execution.

## Why Work Here
- **Mission-Driven Culture**: Focus on accelerating life-changing therapies to patients; work directly impacts patient access and trial efficiency.
- **Values: G.R.I.T.**: The company emphasizes collaboration, curiosity, compassion, resilience, and innovation. Described as a “people-first team of builders.”
- **Benefits**: 75% paid company benefits, 401k with 3% company match, health insurance, life/STD/LTD, and paid time off plus company holidays.
- **Work Environment**: Hybrid/office presence in Cambridge, MA and New York, NY. Open roles span clinical operations, engineering, data science, finance, marketing, and more.
- **Growth Trajectory**: Company is well-funded (Series C, $264M total raised) and actively expanding through acquisitions and headcount, providing career advancement opportunities.

## Sources
1. [iterative.health](https://iterative.health/) – Company homepage, mission, partners, news
2. [iterative.health/about-us](https://iterative.health/about-us/) – Founding story, team, leadership
3. [iterative.health/iterative-health-careers](https://iterative.health/iterative-health-careers/) – Culture, benefits, values
4. [job-boards.greenhouse.io/iterativehealth](https://job-boards.greenhouse.io/iterativehealth) – Current job openings (35 roles)
5. [cbinsights.com](https://www.cbinsights.com/company/iterative-scopes) – Funding history, total raised, stage

## Other roles at Iterative Health

- [Senior Clinical Research Coordinator](https://feeny.ai/job/senior-clinical-research-coordinator-iterative-health-flowood-r4egkaajnqg0) — Flowood, MI
- [Clinical Research Coordinator I -  Memphis, TN](https://feeny.ai/job/clinical-research-coordinator-i-memphis-tn-iterative-health-memphis-czn11v20anvp) — Memphis, TN
- [Clinical Research Systems Specialist](https://feeny.ai/job/clinical-research-systems-specialist-iterative-health-new-york-4msj6c4vqq0e) — New York, NY / Cambridge, MA / Southlake, TX
- [Research Assistant - Mansfield, TX](https://feeny.ai/job/research-assistant-mansfield-tx-iterative-health-mansfield-8t11je9smktf) — Mansfield, TX
- [Clinical Research Coordinator II - Mansfield, TX](https://feeny.ai/job/clinical-research-coordinator-ii-mansfield-tx-iterative-health-mansfield-rv0h9mancmjt) — Mansfield, TX
- [Research Site Manager](https://feeny.ai/job/research-site-manager-iterative-health-providence-7efmg6z2808r) — Providence, RI
- [Director, Activations Strategy and Operations](https://feeny.ai/job/director-activations-strategy-and-operations-iterative-health-new-york-00wne5qx4ftf) — New York, NY / Cambridge, MA / Southlake, TX
- [Clinical Research Coordinator II - Troy, MI](https://feeny.ai/job/clinical-research-coordinator-ii-troy-mi-iterative-health-troy-tve19pph0hqh) — Troy, MI
- [Clinical Research Coordinator I - Webster, TX](https://feeny.ai/job/clinical-research-coordinator-i-webster-tx-iterative-health-webster-3cdvktdfajh7) — Webster, TX
- [Technical Services Engineer – Site Infrastructure & Enablement](https://feeny.ai/job/technical-services-engineer-site-infrastructure-enablement-iterative-health-es1xcmzt13jk) — Cambridge Massachusetts United States New York New York, United States