In Vivo Technical Specialist at Nosis Bio (Alameda, CA)
Nosis Bio· Alameda, CA·
Role details
Job description
About Nosis Bio: Nosis Bio is a well-funded biotech startup exclusively focused on cell-specific delivery of RNA therapeutics. We are an all-scientist team of biologists, chemists, and machine learning experts who believe targeted extrahepatic delivery is the key to making RNA therapies the standard of care for a wide range of chronic diseases. We combine deep expertise in receptor biology, generative AI, and high-throughput in vivo data generation to accelerate the development of RNA therapeutics for new tissues. We are addressing a major unmet need across the industry and actively partner with pharmaceutical companies, research institutions, and biotech companies. About the Role: We are seeking a Technical Specialist / Research Associate to conduct in-vivo experiments to evaluate the pharmacokinetic (PK), pharmacodynamic (PD), and efficacious properties of therapeutic candidates. The successful candidate will have hands-on experience with in-vivo animal studies and will work closely with multidisciplinary teams to support various drug discovery projects. This is an on-site, in person position.
Responsibilities
- Perform in-vivo PK/PD and efficacy studies in animal models, including intravenous (IV) and subcutaneous dose administration, blood sampling, tissue collection, and necropsy.
- Adopt new techniques and develop disease models for in house use.
- Ensure proper animal handling and dosing techniques, following established protocols and ethical guidelines.
- Collect, organize, and document experimental data accurately and maintain laboratory records in compliance with company protocols and regulatory standards.
- Stock/maintain consumables and reagents necessary for experiments.
- Collaborate with cross-functional teams, including biology, chemistry, and translational science, to support project goals and timelines.
What we’re looking for:
- Ability to work on site in our lab spaces located in the California Bay Area – Research park at Marina Village (Alameda, CA)
- Motivated and proactive with strong problem-solving skills.
- Team-oriented and open to collaboration across scientific disciplines.
- Title and track is dependent on academic and professional experience – we recruit diverse backgrounds including those with academic, non-profit, and industry experiences!
- General Requirement: AS or BS degree with 3+ years in vivo experience (industry or academia) and 1+ years experience in an industry (or similar) environment
Why work at Nosis Bio
- Culture: The company emphasizes a culture of "empathy and respect," "first principles thinking," and "failing fast, failing often, and learning." They value patient-centric outcomes and hold themselves to the highest standards of scientific rigor.
- Team: Highly collaborative with a flat structure; the team includes brilliant scientists and engineers across computational, biochemistry, and translational disciplines. As of mid-2026, the team is small (~13 people) but growing rapidly (+46% YoY), offering significant impact and ownership.
- Work Environment: Based in a brand-new, 16,000-square-foot facility in Alameda, CA, equipped for in-house high-throughput biochemistry. The company is on-site (Alameda/Berkeley area), with a focus on wet-lab and computational science collaboration.
- Notable Perks: Opportunity to work at the frontier of AI and biology; direct exposure to major pharma partnerships (J&J, Daiichi Sankyo); early-stage equity potential in a high-growth startup; a mission-driven focus on curing chronic disease.