Head of Commercial at Boltz (London, United Kingdom)
Boltz· London, United Kingdom·
Role details
Job description
About Boltz
Boltz is a public benefit company building the next generation of AI-powered molecular modeling tools to make biology programmable and accelerate drug discovery, while keeping frontier capabilities broadly accessible.
Boltz-1, Boltz-2, and BoltzGen are open models trusted by 100,000+ scientists across biotech and academia, and used in programs at every Top 20 pharma as well as leading agrichemical and industrial research organizations.
We deliver these capabilities through Boltz Lab, our platform for running our latest models and design agents as reliable, production-grade tools. Boltz Lab is designed around real chemistry and biology workflows, so teams can start from a target and a hypothesis and quickly generate, evaluate, and rank candidate molecules.
About the role
As Head of Commercial, you will own Boltz’s enterprise commercial motion, converting inbound interest from leading pharma and biotech organizations into large, structured platform partnerships.
Boltz already has a strong top-of-funnel driven by scientific credibility and open-source adoption. Your role is to translate that demand into $1M+ ACV enterprise contracts, deploying Boltz models into secure customer environments and structuring long-term collaborations.
You will operate as a player-coach: personally leading high-value deals while building a repeatable enterprise sales motion. This includes scoping complex engagements, negotiating contracts, and expanding key accounts over time.
You will work closely with the CEO, scientific leadership, and product to ensure that commercial engagements are grounded in real scientific value and aligned with Boltz’s long-term platform vision.
About you
Essentials:
- 5+ years of experience in sales or business development with a proven track record closing multimillion dollar enterprise deals in frontier technology (ideally software)
- Comfortable leading sales and building sales function from scratch
- Strong technical fluency - able to engage credibly with ML, infrastructure, and product teams
- Ability to convert warm inbound demand into structured, closed deals without heavy SDR support
- Excellent communication, negotiation, and stakeholder management skills
Nice to have:
- Experience in life sciences, biotech, or pharma
- Background at companies deploying AI tools into enterprises
- Existing network across large pharma and biotech organizations
- Experience deploying products into secure or VPC environments
What we offer:
- Opportunity to define the commercial strategy of a category-defining AI platform
- Direct ownership of high-value enterprise relationships across global pharma
- Significant autonomy and influence at company level
- Highly competitive compensation with substantial equity
Why work at Boltz
- Culture: Mission‑driven, open‑science ethos with a strong emphasis on research excellence and product impact. The team is lean (~17 employees as of early 2026) and growing.
- Remote/Hybrid: Not explicitly stated; locations include London (HQ) and Boston. Likely flexible given the global team (employees in UK, US, Netherlands, Switzerland).
- Notable perks: Opportunity to work on frontier AI models used by 100k+ scientists; direct collaboration with top pharma; usage‑based pricing aligns with customer success; public‑benefit status ensures long‑term mission alignment.
- Engineering culture: Heavy focus on research engineering, software engineering, and product design. Looking for protein engineers with preclinical experience to shape the product roadmap.